Pattern electroretinogram losses underlying perimetric losses in early glaucoma
نویسندگان
چکیده
منابع مشابه
Ganglion cell losses underlying visual field defects from experimental glaucoma.
PURPOSE To investigate the relationship between ganglion cell losses and visual field defects caused by glaucoma. METHODS Behavioral perimetry and histology data were obtained from 10 rhesus monkeys with unilateral experimental glaucoma that was induced by argon laser treatments to their trabecular meshwork. After significant visual field defects had developed, the retinas were collected for ...
متن کاملPhotopic negative response versus pattern electroretinogram in early glaucoma.
PURPOSE Photopic negative response (PhNR) and pattern electroretinogram (PERG) are electrophysiological markers of retinal ganglion cell function; both are reduced in glaucoma. We compared PhNR and PERG in different stages of the disease. METHODS Eleven eyes with preperimetric glaucoma (glaucomatous optic disc with normal field); 18 with manifest glaucoma; and 26 normals were included. We obt...
متن کاملThe multifocal pattern electroretinogram in glaucoma
BACKGROUND The pattern ERG can be used to detect early glaucomatous change, because the response of cells in the inner retina from (typically) 20 degrees -40 degrees of area is reduced before perimetric abnormality is certain. The multifocal pattern electroretinogram (mfPERG) allows analysis of many local regions within this area. The aim of this study was to investigate whether in patients wit...
متن کاملUpdate on the pattern electroretinogram in glaucoma.
PURPOSE To review the efficacy of the pattern electroretinogram (PERG) in early diagnosis of glaucoma. METHODS Stimulation parameters of check size and temporal frequency are considered. Analyses of various peaks (P50, N95, the N95/P50) and Fourier steady-state are considered. The relation to visual field defects is explored. RESULTS The PERG is markedly alterated in glaucoma. It shows ampl...
متن کاملIdentifying Cell Class Specific Losses from Serially Generated Electroretinogram Components
PURPOSE Processing of information through the cellular layers of the retina occurs in a serial manner. In the electroretinogram (ERG), this complicates interpretation of inner retinal changes as dysfunction may arise from "upstream" neurons or may indicate a direct loss to that neural generator. We propose an approach that addresses this issue by defining ERG gain relationships. METHODS Regre...
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ژورنال
عنوان ژورنال: Acta Ophthalmologica Scandinavica
سال: 2002
ISSN: 1395-3907
DOI: 10.1034/j.1600-0420.80.s236.17.x